Though most of the research for the virus took place within the Arklay Laboratory underneath the Spencer estate façade, some eight miles North-west of Raccoon City, and the Umbrella Training facility under Marcus' orders, covered by the American Umbrella offices, Spencer's Umbrella empire in Europe raced against Marcus to adequate the t-virus to create a virus with an even greater destructiveness. Marcus' dreams to overthrow Spencer and his attitude towards the virus as a "money-spinning tool" for Umbrella were never fulfilled, as he was murdered before he could enact them. Birkin came to be known within Umbrella circles as the true creator of the t-virus.[5]
During those years, vast numbers of t-viral strains were developed in the Arklay Laboratory, and tested upon one solitary test subject: Lisa Trevor. For years, she was subject to intense biological torture, which, despite all odds, she survived.
As well, William Birkin, grown conceited as being credited as the creator of the t-virus,[6][7] spawned a myriad of biological weapons to serve as backup to the virus, to ensure a 100% death ratio in any populace the virus should be released. Among these are the Hunters (created by fusion of a human fertilized egg with t-virus infected reptilian DNA),[8] the Ivies (flowers grown to unnatural proportions and given animal instincts, locomotion and rudimentary defence mechanisms),[citation needed] the Chimeras (a mixture between a fly and human given vague humanoid appearance, increased size and mass, improved claws, and better reflexes),[citation needed] the Cerberus (infected dogs - specifically Dobermans), and most importantly, the crowning achievement of Birkin's career for the time: the Tyrant.
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